A549-hSERPING1-EGFP_OE (Puro)


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  • 细胞图0 SERPING1 Stable Expression Cell Line (A549)-细胞图0
  • 细胞图1 SERPING1 Stable Expression Cell Line (A549)-细胞图1
  • 质粒图0 SERPING1 Stable Expression Cell Line (A549)-质粒图0
  • A549-hSERPING1-EGFP_OE (Puro) SERPING1 Stable Expression Cell Line (A549)-产品图
SERPING1 Stable Expression Cell Line (A549) 一键复制产品信息
货号: YOE-L039
价格: 6000元
规格: 1*10^6
培养体系: 90% F12K+10% FBS
  • 细胞图0 SERPING1 Stable Expression Cell Line (A549)-细胞图0
  • 细胞图1 SERPING1 Stable Expression Cell Line (A549)-细胞图1
  • 质粒图0 SERPING1 Stable Expression Cell Line (A549)-质粒图0
  • A549-hSERPING1-EGFP_OE (Puro) SERPING1 Stable Expression Cell Line (A549)-产品图
SERPING1 Stable Expression Cell Line (A549) 一键复制产品信息
货号: YOE-L039
价格: 6000元
规格: 1*10^6
培养体系: 90% F12K+10% FBS

产品详情

细胞基本信息

产品货号 YOE-L039 转录本 NM_000062.3
细胞名称 SERPING1 Stable Expression Cell Line (A549) 物种 Human
基因名称 SERPING1 传代比例 1:3~1:4
细胞形态 上皮样, 贴壁细胞 药筛浓度 Puro=1μg/ml
培养体系 90% F12K+10% FBS 支原体检测 阴性
产品货号
YOE-L039
细胞名称
SERPING1 Stable Expression Cell Line (A549)
基因名称
SERPING1
细胞形态
上皮样, 贴壁细胞
传代比例
1:3~1:4
转录本
NM_000062.3
物种
Human
药筛浓度
Puro=1μg/ml
支原体检测
阴性
培养体系
90% F12K+10% FBS
*本产品仅供进一步科研使用,不得用于诊断、治疗、临床及其它用途。

基因简介

This gene encodes a highly glycosylated plasma protein involved in the regulation of the complement cascade. Its encoded protein, C1 inhibitor, inhibits activated C1r and C1s of the first complement component and thus regulates complement activation. It is synthesized in the liver, and its deficiency is associated with hereditary angioneurotic oedema (HANE). Alternative splicing results in multiple transcript variants encoding the same isoform.
基因简介
基因表达验证
No. Sample hSERPING1-1CтMean β-h_actin CтMean ΔCтMean ΔΔCт Expression Rate
1 SERPING1 Stable Expression Cell Line (A549) 21.464 13.664 7.800 -7.418 171.017
2 A549_Ctrl(Puro) 28.944 13.726 15.218 0.000 1.000
STR 鉴定
Loci 送检细胞STR信息
送检细胞名:A549
细胞库细胞STR信息
细胞库细胞名:A-549
Allele1Allele2Allele3Allele1Allele2Allele3
D5S818 11111111
D13S317 11111111
D7S820 811811
D16S539 11121112
VWA 14141414
TH01 89.389.3
AMEL XYXY
TPOX 811811
CSF1PO 10121012
D12S391 1818
FGA 2323
D2S1338 2424
D21S11 2929
D18S51 1417
D8S1179 1314
D3S1358 1616
D6S1043 1113
PENTAE 711
D19S433 1313
PENTAD 99
D1S1656 1718.3
* 该细胞系与收录于ATCC, DSMZ, JCRB 和 RIKEN数据库的细胞系STR数据匹配。
结论:该细胞 STR 鉴定正确。

产品优势

  • icon
    表达量高
    采用独家细胞筛选技术确保表达量高,提供RT-qPCR验证数据。
  • icon
    稳定性好
    基因拷贝数稳定,细胞代次低,能够稳定传代20代以上。
  • icon
    质检严格
    执行严格的质量控制,确保无细菌支原体污染,并通过STR身份验证以及细胞复苏活率测试,高标准交付。
产品引用文献:

[1] Yao, Jie, et al. "Long noncoding RNAs AC026904. 1 is essential for TGF‐β‐induced migration and epithelial‐mesenchymal transition through functioning as an enhancer of Slug in lung cancer cells." Environmental toxicology 35.9 (2020): 942-951.

[2] Roussel, L., Pham-Huy, A., Yu, A.C. et al. A Novel Homozygous Mutation Causing Complete TYK2 Deficiency, with Severe Respiratory Viral Infections, EBV-Driven Lymphoma, and Jamestown Canyon Viral Encephalitis. J Clin Immunol 43, 2011–2021 (2023).

[3] Khaodee,et al. "Transcriptomic analysis of glucosidase II beta subunit (GluIIß) knockout A549 cells reveals its roles in regulation of cell adhesion molecules (CAMs) and anti-tumor immunity." BMC Genomics 25, 82 (2024).

[4] Ding, Rui, et al. "TLR2 regulates Moraxella catarrhalis adhesion to and invasion into alveolar epithelial cells and mediates inflammatory responses." Virulence 15.1 (2024): 2298548.

[5] Yaman, Serkan, et al. "Targeted chemotherapy via HER2-based chimeric antigen receptor (CAR) engineered T-cell membrane coated polymeric nanoparticles." Bioactive Materials 34 (2024): 422-435.

[6] Wang, Liuxiang, et al. "DEPDC1 is a potential therapeutic target in lung adenocarcinoma." Nano Today 56 (2024): 102249.

[7] Wang, Juhong, et al. "Acetate reprogrammes tumour metabolism and promotes PD-L1 expression and immune evasion by upregulating c-Myc." Nature Metabolism (2024): 1-18.

产品货号:YOE-L039
产品名称:SERPING1 Stable Expression Cell Line (A549)

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