名 称 | 描 述 | 组织特异性 | 细胞类型特异性 | 参考文献 |
---|
Nes | Rat nestin intron 2 enhancer fused to mouse Hsp68 minimal
promoter | Nervous system at embryonic stage | Neural stem/pro-genitor cells | Eur J Neurosci. 9:452 (1997); J Neurosci Res. 59:321
(2000) |
Camk2a_short | Mouse α-calcium-calmodulin dep-endent kinase II promoter
(1.3 kb) | Brain | Pyramidal neurons | Neuroscience. 161:441 (2009) |
SYN1 | Human synapsin I promoter | Brain | Mature neurons | Mol Ther. 5:509 (2002) |
Nes | Rat neuron-specific enolase promoter | Nervous system | Various neurons | Neuron. 5:187 (1990); J Mol Neurosci. 8:63(1997) |
GFAP_short | Human glial fibrillary acidic protein promoter (0.68 kb) | Brain | Astrocytes | Glia. 56:481 (2008) |
K14 | Human keratin 14 promoter | Epidermis | Keratinocytes | Gene. 153:297 (1995) |
cTnT | Chicken cardiac troponin T promoter | Heart | Cardiomyocytes | Am J Physiol Cell Physiol.
286:C556 (2004); Gene
Ther. 18: 43 (2011);
Circ Res. 115:354 (2014) |
alphaM-HC_short | Mouse α-cardiac myosin heavy chain promoter (2.8 kb) | Heart | Cardiomyocytes | Neuroscience. 161:441 (2009) |
Myog | Mouse myogenin promoter | Muscle | Myoblasts | Genes Dev. 7:1277 (1993) |
MHCK7 | Composed of enhancer/promoter
regions of murine muscle creatine
kinase (MCK) and enhancer region
of α-myosin heavy-chain genes. | Genes Dev. 7:1277 (1993) | Differentiated postmitotic stria-ted muscle cells | Mol Ther. 15:320 (2007); Sci Transl Med. 9(418) (2017) |
SM22a | Mouse transgelin (a.k.a. Sm22a) promoter | Adult smooth muscle | Vascular smooth muscle cells | J Cell Biol. 132:849 (1996) |
EnSM22a | The chimeric vascular smooth
muscle-specific enhancer/promoter
(The rabbit myosin heavy-chain enh-
ancer inserted upstream of a
truncated mouse SM22a promoter) | Adult smooth muscle | Vascular smooth muscle cells | J Pharmacol Exp Ther. 329: 775 (2009) |
Tie1 | Mouse tyrosine kinase with
immunoglobulin-like and
EGF-like domains 1 promoter | Blood vessel | Endothelial cells | J Cell Sci. 115:2075 (2002) |
CD68_short | Human CD68 promoter, short,
recommended for in vitro use | Blood | Monocytes and
macrophages | Gene Ther. 19:1041 (2012) |
Alb | Mouse albumin promoter | Liver | Mature
hepatocytes | Genes Dev. 1:268 (1987) |
TBG | Human thyroxine-binding
globulin promoter | Liver | Hepatocytes | Gene. 506:289 (2012) |
MMTV | Mouse mammary tumor
virus long terminal repeat (LTR) | Mammary gland | Ductal cells of the salivary gland, mammary epithelial
cells | Nucleic Acids Res. 25:4323 (1997) |
HIP | Human insulin promoter | Pancreas | β cells | Cell. 52:773 (1998); Proc Natl Acad Sci U S A. 100: 6688
(2003) |
Pdx1 | Mouse pancreatic and duodenal homeobox 1 promoter | Embryonic develo-ping pancreas and adult pancreatic
islets | Pancreatic proge-nitor cells and pancreatic β cells | Development. 129:2447 (2002) |
SP-B | Human surfactant protein B promoter | Lung | AT II cells (alveolar
type II epithelial
cells) and Clara
cells (bronchiolar
epithelial cells) | J Biol Chem. 270:24852
(1995); Gene Ther.
14:1461 (2007) |
CD144 | Human cadherin 5
(a.k.a. VE-Cadherin) promoter | Lung, heart, ovary,
spleen and kidney
glomeruli | Vascular
endothelial cells | Oncogene. 24:2992 (2005) |