SERPING1 Stable Expression Cell Line (NCI-H520)
This gene encodes a highly glycosylated plasma protein involved in the regulation of the complement cascade. Its encoded protein, C1 inhibitor, inhibits activated C1r and C1s of the first complement component and thus regulates complement activation. It is synthesized in the liver, and its deficiency is associated with hereditary angioneurotic oedema (HANE). Alternative splicing results in multiple transcript variants encoding the same isoform.
| No. | Sample | hSERPING1-2CтMean | β-h_actinCтMean | ΔCтMean | ΔΔCт | Expression Rate |
|---|---|---|---|---|---|---|
| 1 | SERPING1 Stable Expression Cell Line (NCI-H520) | 14.994 | 15.138 | -0.144 | -11.165 | 2296.148 |
| 2 | NCI-H520_Ctrl(Puro) | 27.899 | 16.878 | 11.021 | 0.000 | 1.000 |
本产品仅供进一步科研使用,不得用于诊断、治疗、临床及其他用途。
拆箱和存放说明
细胞复苏、传代及冻存流程概述参考
EZ-iScreen™产品优势
该类细胞株稳定表达Cas9蛋白,仅需转染gRNA,即可实现基因敲除,而同时转染gRNA和供体DNA,则可实现基因敲入/点突变。
在该类细胞的基础上已成功构建大量基因敲除细胞株,且基因敲除效率均提高5-10倍。
该类细胞株经过优化,代次低、活性高、状态好,适用于各类基因编辑实验。
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